If you’re living in Southport, Beech Grove, or anywhere on the south side of Indy, the Home Depot at 4850 E Southport Rd is basically the local headquarters for getting things done. Located right off I-65, it’s the go-to spot for those of us who would rather spend a Saturday morning fixing up the house than fighting the heavier traffic up toward the North Side. It’s a massive, high-energy warehouse, but it still has that neighborhood vibe where you’re just as likely to run into a neighbor in the plumbing aisle as you are a local contractor grabbing a coffee at sunrise.
What really makes this "Southport" branch a lifesaver is the Tool & Truck Rental Center. We all know that in some of our cozy suburban neighborhoods, garage space is a luxury, so there’s no point in buying a giant power auger or a floor sander that you’ll only use once every five years. You can just rent the pro-grade gear for a few hours, knock out your project, and bring it back. Plus, if you’re picking up something that definitely won’t fit in your SUV—like a new riding mower or a stack of lumber for a deck repair—they have rental trucks right on-site to help you get your haul home without the headache.
The Garden Center here is another local favorite, especially when the Indiana seasons start to shift. It’s the first place we head to grab heavy-duty snow shovels and bags of salt before a Hoosier winter storm hits, and it’s the best spot to find hardy plants that can actually survive a humid 90-degree July. The staff—especially the folks at the Pro Desk—actually understand the specific needs of our local homes. Whether you’re looking for a specific part for an older home repair or need advice on the best grass seed for Indiana soil, there’s usually an "Orange Apron" around with a practical, no-nonsense tip.
For those days when you’re in a real rush to beat the traffic near the Emerson Ave intersection, the Home Depot app and Curbside Pickup are total game-changers. You can check exactly which aisle and bay your door hinges are in before you even park, or just order online and have the team bring your items right out to your vehicle near the front. It’s efficient, reliable, and run by a crew that knows how to get people in and out so they can get back to their projects. Whether you're a professional builder hitting the aisles at 6:00 AM or a DIYer tackling your first kitchen backsplash, this Southport spot is the anchor that gets the job done.
Business Hours
Monday – Saturday: 6:00 AM – 10:00 PM
Sunday: 8:00 AM – 8:00 PM (Note: Curbside pickup is generally available from 9:00 AM – 6:00 PM. The Pro Desk and Rental Center typically open at 6:00 AM on weekdays, which is perfect for the "early bird" crew to beat the morning commute.)
When The Home Depot was founded in 1978, Bernie Marcus and Arthur Blank had no idea how revolutionary this new “hardware store” would be for home improvement and the retail industry.
Today, we’re proud to be the world’s largest home improvement retailer. In more than 2,300 stores across North America, we aspire to excel in service – to our customers, associates, communities and shareholders. That’s what leadership means to us. That's The Home Depot difference.
Our founders' vision of one-stop shopping for the do-it-yourselfer came to fruition when they opened the first two Home Depot stores on June 22, 1979, in Atlanta, Georgia. The first stores, at around 60,000 square feet each, were cavernous warehouses that dwarfed the competition and stocked 25,000 products, much more than the average hardware store at that time.
Today, The Home Depot is the world's largest home improvement retailer with approximately 475,000 orange-blooded associates and more than 2,300 stores in the U.S., Canada and Mexico. The typical store today averages 105,000 square feet of indoor retail space, interconnected with an e-commerce business that offers more than one million products for the DIY customer, professional contractors, and the industry's largest installation business for the Do-It-For-Me customer.
